Tissue Engineering is the most promising in artificial organ research

I have a great interest for science in terms of innovation. And inside this subject, one of the most things that calls my attention is the creation of new organs. 

I started a discussion on Reddit about this subject, asking what stage we are in the development of such work.

After all, the fact that tissue engineering is the one with most promise results was clear. Resources about this subject say:

Success reported in growing functioning liver tissue in a bioreactor

For example, even if we couldn’t recreate a liver with all its functionalities, by recreating the tissue, it would make the work for itself, as mentioned on the discussion linked above:

…so even if your liver did some functionality very unique to you, it would still be able to replicate that process once the liver was transplanted inside.

All of this, thanks for the tissue engineering.

It’s a great subject to be explored and very interesting to be known.

posted 1 month ago

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The Rise of the Open Science

Open science is opening the way we make science. It stands for transparency and public accessibility of scientific data, collaboration, methods and results. On the other hand, it supports the existence of public contribution to the current state of science, and giving it back to the public domain.

Motivation

While we are making science, we rely on the older publications and methods those are often published with no open access to data. Years ago, academic community skeptically started to question the credibility of the research work on the existing literature. The way that science is funded was one of chief reasons behind this question. Science made with non-open data had possibility to be easily led by politics and other funding authority such as private companies to mislead the facts such as global warming or medical side-effects of a new medicine. Firing up an openness discussion led another ideas such as opening the methods and scientific source code.

Why to open data, open tools and open results?

One of the core values of science was being open and accessible. But ironically science is today receive heavy financial support from private institutions and governments where much of the budgets are shaped by economical, industrial or military needs. Scientific institutions are mostly closed to people without PhDs for scientist roles because there is already a huge competition among PhDs. Our credibility is measured by the number of papers published and number of citations we receive. I wouldn’t want to slander scientists but professional science, as in its own closed ecosystem, has a few conflicts against the key foundations of science. Science’s route, subject, people and results are controlled or may have possibility of being controlled by authority. In next few decades, we have to reissue the way we sustain  science.

We also do have a verification problem with science that relies on data. Computational and statistical science is lacking in reproducing the final results advertised on publications. JASA (Journal of the American Statistical Association) reports that only 21% of the papers are being published with source open in 2011, still a positive number compared to 2006′s 9%. Without code or data, even the work is published on an academic journal, there is no way to validate or iterate over the existing founding.

One of the key problems as we can address is that scientific research is not maintainable without economical sustainability due to the need of scientific tools. I’ve watched Eri Gentry, the founder of BioCurious, at OSCON last year. Her key points about opening the scientific tools, in the self-makers’ vision was motivating. According to her, at some point at BioCurious, they needed to have a PCR machine that was costing several thousand dollars to keep their garage based research on. Since they can’t afford the machine, they decided to analyze how they are actually working. Fortunately, they’ve figured out what it’s about and created OpenPCR. And now you are able to copy some strawberry DNA sequence or make cancer research at home. An open repository of knowledge on making scientific tools will increase the level of collaboration from regular makers and DIY people who may never have chance to investigate or be able to reverse engineer these tools.

Collaborative Science

By the radical changes in means of communication, discovery and discussion will have to change radically as well. A few months ago, I’ve seen a book by Michael Nielsencalled Reinventing Discovery: The New Era of Networked Science on the new arrivals section. Nielsen opens the first chapter by a 2009 story about Tim Gowers‘ Polymath Project. Tim Gowers is a very notable mathematician, a Fields medalist from Cambridge University. In 2009, instead of working alone or with his existing pairs, he decided to discuss a mathematical problem on his blog and asked for readers to share their ideas online. In 6 weeks, he received 800 comments from 27 people. Although start has a its pitfalls, 37 days later Gowers announced they have not just solved his problem but the generalization of the polymaths problem including a special case.

And what about citizen science? Citizen science is used to be perceived as a more pro way of scientific crowd sourcing. But this perception seems to be changing. Very recently, I had a few discussions with friends who are totally aliens for citizen science and its current initiatives. They preliminary questioned the need of citizen scientists. Our main talk was about classification of galaxies on GalaxyZoo. GalaxyZoo is an online tool that shows you images of galaxies taken by Hubble telescope and wants you to manually choose if galaxy is elliptical or spiral or it has some set of features or not. Any programmer would initially ask why we are doing this classification manually in 2010s. Honestly, we have technology to pick up the features directly from signal without any observation from a human eye. So? But, discovery is not classification. We actually don’t know what we are looking at. Any anomalies or any strange looking objects would be a new scientific discovery. By reviewing the existing images, GalaxyZoo members discovered a new type of galaxies, now we call them “pea galaxies” and Hanny van Arkel, a Dutch school teacher, discovered a green strange nebula-looking object in the size of the Milky Way Galaxy called Hanny’s Voorwerp again in 2007.

So, why aren’t we taking it any further? There is an ongoing afford to make a cultural shift to increase the awareness and participation into science. Not only Zooniverse projects but NASA has opened code.nasa.gov very recently. Ariel Waldman is keeping a dictionary of all citizen space exploration projects onspacehack.org for a while. LHC’s ongoing CMS project donated data to Science Hack Day participants to let data hackers come up with data visualization tools for CMS. DIYgenomics are crowd sourcing genomic data. The list goes on…

Conclusion

With the ongoing momentum in scientific communities, in the next few decades, we’ll experience a tremendous change in they way we make and participate in science. For now, not intercepting conventional means but creating possibilities, new science is approaching with the strong sympathy for making scientific results freely and universally accessible.

(Source: burcudogan.com)

posted 1 month ago

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Some changings might be coming to #Pixel Language - Please read!

Due to some discussions of how to make this language better in its syntax, and etc, a good approach has been proposed by willbr, in which he proposes to mix its syntax with Python syntax but with Lisp like operators, which you see here.

I thought it really interesting, due to the fact that its more easy to be implemented and also it will have a better “readable” property. I’m really thinking about changing its syntax to this approach, and I’m considering the risks and studying the time to reimplement the compiler with its new features.

However, any changes will be notified here. Please tell me what do you think about this new approach.

Fell free to help improve Pixel!

posted 1 month ago

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A big revolution is going out there!

This goes to young developers/startup founders, dreamers, etc..

When I say a revolution is going out there, I mean a lot of things is going beside us that we don’ t see. Since the launch of mobile devices, now we can see the TV’s by Apple and Google, etc. Also engines for based on your interest, like StumbleUpon, eBooks, etc.. I mean, evertyhing that has been launched and are simple stuff, makes a big revolution in our lifes. 

It is much easier to start a web startup in 2011 than it was in 1995, or even 2005.

You don’t need upfront capital to buy racks of machi­nes, miles of CAT-5, routers and load balancers, redun­dant power and backbone connec­tivity — all are avail­able on-demand from Amazon for pennies an hour.

With all this technologies and numbers of ideas, motivations, etc, its “easy” to have your idea and monetize it. (When I say easy, not in the way that is really easy - I mean, you will face a lot of problems, etc - but in a way that anyone can do it). At least, in my own experience, eight months ago, I started developing an idea that I had while on university, so I started developing with my brother (I worked on mobile side and my brother worked on server side), and we are feeling so crazy about it, all we see is a lot of young guys launching their projects and people commentin/using it, etc.. And the anxious is so strong when we see this and our idea is still under development, because its so important for us, to see people using our software (because we know this will help them). 

Whatever, this was just a relief. =)


However, as some people believe, to create your startup and work on an idea you had and to have success with ittalent is required.

Mentioning again, a true fact about the post linked before:

But ask any startup around what they really do need right now, and the answer is clear —great technical talent. Startups of all sizes are competing for a small pool of highly skilled candi­dates, and in startup hubs like San Francisco and New York the compe­ti­tion for engineers is fierce. This scarcity has persisted despite consis­tently high national unemployment rates.

This post really deservers a ‘+1’, ‘Like’, ‘Tweet’ or whatever… 

IDK what to say anymore, all I know is that I don’t want to be out of this revolution, this movement going around us, I don’t want just seat and watch as a common user, I want to provide to the users something cool (and I believe - as a lot of people - I’m developing such a cool project).

IDK if you can understand what I want to say here, but, just, think about it, and try to see what is going on around us.


May the force be with you.

posted 1 month ago

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Issues when creating a product/invention.

The life of an inventor is not an easy one. First you have to come up with a good idea that solves a problem in a way that no one has thought of before, and then you need to design and engineer your idea to take it from theory to reality. The very nature of invention means that inventors are continuously pushing the boundaries of what’s possible. This drive to discover the next Big Thing has been a boon to humanity and has given us inventions like the steam engine, the automobile and the personal computer.

Here is a post of something that really made me think, and I identified my self with this guys. 

After this, let me go back to my work while I listen to Supertramp.

posted 2 months ago

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My first article on Substance.io for #android developers

I started my first article on Substance.io as an article with useful tips for Android developers. This article will be built step by step, constantly I will be updating new content and useful tips there.

By now you can check the version 1.0 of it clicking here.

Enjoy!

posted 2 months ago

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#HTML5 Rocks! A reblog.

HTML5 introduces many cutting-edge features that enable developers to create apps and websites with the functionality, speed, performance, and experience of desktop applications. But unlike desktop applications, apps built on the web platform can reach a much broader audience using a wider array of devices. HTML5 accelerates the pace of your innovation and enables you to seamlessly roll out your latest work to all your users simultaneously.

So here is the link to the original post from html5rocks. Enjoy!

posted 3 months ago

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Moving articles post to Substance.io

I’m officially moving all of my articles post fo Substance.io, a great platform for document authoring and publishing. Mainly because the platform is great for article post and for write about coding and stuff, also because Tumblr is not a platform specifically and optimized for blogging about coding etc.

So basically, this Tumblr will be used for posting random stuff, mainly of my interest etc. 

You can check my profile on Substance.io and if you have interest in posting your own documents, you should create an account there and start posting.

Also Substance.io is an open source platform, so you can get the source code here.

That’s it. See you on Substance.io!

posted 3 months ago

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brycedotvc:

In her final episode, Oprah was asked if there was a common thread throughout her 25 years on the air. As she reflected on decades of interactions and interviews she distilled it down to one thing all of here guests shared:

I’ve talked to nearly 30,000 people on this show, and all 30,000…

posted 4 months ago

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